(1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. If you have recently had a head injury or a heart attack. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. If you have an underactive thyroid gland. This survey is being conducted by the WebMD marketing sciences department. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. All rights reserved. Things to remember when you fill your prescription. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Mehta D. Herbal & dietary supplements. Making any changes without doctor's advice can be dangerous. Conclusions: In Canada - Call your doctor for medical advice about side effects. These side effects may go away during treatment as your body adjusts to the medicine. The information on this page is written and peer reviewed by qualified clinicians. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. FOIA Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Accessibility Unless your doctor tells you otherwise, continue your normal diet. Talk to your pharmacist for more details. To use the sharing features on this page, please enable JavaScript. AHFS Patient Medication Information. 2010; doi:10.1016/j.jacc.2009.07.074. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). The Swedish Multicentre Group. This document does not contain all possible drug interactions. Nitroglycerin has an average rating of Canada residents can call a provincial poison control center. Copyright 2023 IBM Watson Health. Does Alcohol Raise Your Blood Pressure? . This should pass after a few days. Isosorbide mononitrate helps to prevent angina chest pain from developing. Danshen. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. Natural Medicines. Available for Android and iOS devices. It might help to keep the room cool and use a fan. Methods: 72% of reviewers reported a positive effect, while 12% reported a negative effect. information and will only use or disclose that information as set forth in our notice of Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. Careers. On the other hand, the ER version can only help prevent angina. MBBS, MS - General Surgery, mch neuro surgery. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. This information is aggregated and used to produce personalized reports that patients can reference. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. What side effects can this medication cause? Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. eCollection 2021. The table below contains some of the most common ones associated with isosorbide mononitrate. View all Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Data were assessed for carryover and time effects. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Overview of herbal medicines and dietary supplements. https://naturalmedicines.therapeuticresearch.com. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. View interaction reports for isosorbide mononitrate and the medicines listed below. Many people using this medication do not have serious side effects. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Some don't work well with prescription medicines. In case of overdose, call the poison control helpline at 1-800-222-1222. Am J Ther. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). Prescription and OTC It has a very short duration of action and may not be suitable for some people. What special precautions should I follow? Do not take a double dose to make up for a missed one. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Elsevier; 2021. https://www.clinicalkey.com. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with heart failure. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Isosorbide mononitrate is very similar to isosorbide dinitrate. Ask your pharmacist any questions you have about refilling your prescription. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. Unless there is a specific reason you need the brand, the generic medication will be a better value. Side effects : headache, mild dizziness Mayo Clinic does not endorse companies or products. This product is available in the following dosage forms: There is a problem with Truven Health does not assume any responsibility or risk for your use of the Truven Health products. 7.6 out of 10 from a total of https://naturalmedicines.therapeuticresearch.com. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. Take isosorbide exactly as directed. Do not stop taking it without consulting your doctor. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). People with kidney problems should be able to take the usual dose of isosorbide mononitrate (Monoket). Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Patient does not provide medical advice, diagnosis or treatment. You may report side effects to Health Canada at 1-866-234-2345. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. National Library of Medicine Bookshelf prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Properly discard this product when it is expired or no longer needed. (2) One in 3 patients never experienced headache from the given dosages. No you may not. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Select a condition to view a list of medication options. The IR version can help treat and prevent angina. 19 are major, 174 are moderate, and 2 are minor. The https:// ensures that you are connecting to the Contraindications: Isosorbide mononitrate should not be used in cases of acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or hypertrophic obstructive cardiomyopathy (HOCM), constrictive pericarditis, low cardiac filling pressures, aortic/mitral valve stenosis and diseases associated with a raised intra-cranial pressure e.g following a head trauma and including cerebral haemorrhage. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Consult your doctor for more details. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Ask your doctor before using aspirin together with alcohol. What are the side effects of Isosorbide Mononitrate ? Results: Browse all drugs on eHealthMe. It might help to take isosorbide mononitrate and dinitrate after meals. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. Upgrade to Patient Pro Medical Professional? Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . Background: Isosorbide mononitrate (Monoket) is a nitrate vasodilator. flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. Generic alternatives may be available. Herbal supplements are natural, so they must be safe, right? Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. It works to relax your blood vessels. from the best health experts in the business. A single copy of these materials may be reprinted for noncommercial personal use only. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. Tolerance is more likely to happen if you don't take your dose at the same time every day. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication.

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